Analysis of polymorphisms affecting immune complex handling in systemic lupus erythematosus

Objectives. Systemic lupus erythematosus (SLE) is a polygenic disorder of dysregulated inflammation. Numerous specific candidate genes have been identified and most relate to the handling of immune complexes or antigen presentation. This is consistent with the classic finding of immune complex depos...

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Veröffentlicht in:	British journal of rheumatology 2003-03, Vol.42 (3), p.446-452
Hauptverfasser:	Sullivan, K. E., Jawad, A. F., Piliero, L. M., Kim, N., Luan, X., Goldman, D., Petri, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigen-Antibody Complex - metabolism Biological and medical sciences Black or African American Black People Complement System Proteins - genetics Female Gene Frequency Humans Logistic Models Lupus Erythematosus, Systemic - ethnology Lupus Erythematosus, Systemic - genetics Lupus Erythematosus, Systemic - immunology Male Medical sciences Odds Ratio Polymerase Chain Reaction Polymorphism, Genetic Prospective Studies Receptors, IgG - genetics Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis White People
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