Specificity of Porcine Calcitonin Receptor and Calcitonin Receptor-like Receptor in the Presence of Receptor-Activity-Modifying Proteins

Adrenomedullin (AM), calcitonin gene-related peptide (CGRP), amylin (AMY) and calcitonin (CT) are members of the CGRP/CT superfamily of peptides. Among them, AM and CGRP are reported to share a core receptor, the calcitonin receptor-like receptor (CRLR), and the specificity of the CRLR is determined...

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Veröffentlicht in:	Hypertension Research 2003, Vol.26(Suppl), pp.S15-S23
Hauptverfasser:	KIKUMOTO, Katsuro, KATAFUCHI, Takeshi, MINAMINO, Naoto
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenylyl Cyclases - metabolism Adrenomedullin Amino Acid Sequence amylin Amyloid - pharmacology Animals Calcitonin - pharmacology calcitonin gene-related peptide Calcitonin Gene-Related Peptide - pharmacology Calcitonin Receptor-Like Protein calcitonin receptor-like receptor Cloning, Molecular COS Cells Cyclic AMP - metabolism DNA, Complementary Enzyme Activation - drug effects Intracellular Signaling Peptides and Proteins Islet Amyloid Polypeptide Membrane Proteins - genetics Membrane Proteins - metabolism Molecular Sequence Data Peptides - pharmacology Rats Receptor Activity-Modifying Protein 1 Receptor Activity-Modifying Protein 2 Receptor Activity-Modifying Protein 3 Receptor Activity-Modifying Proteins receptor-activity-modifying protein Receptors, Calcitonin - genetics Receptors, Calcitonin - metabolism Sequence Homology, Amino Acid Swine Transfection Vasodilator Agents - pharmacology
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