Hypoxemia and reoxygenation with 21% or 100% oxygen in newborn pigs : changes in blood pressure, base deficit, and hypoxanthine and brain morphology

To study whether room air is as effective as 100% O2 in resuscitation after hypoxia, hypoxemia (PaO2 2.3-4.3 kPa) was induced in newborn pigs (2-5 d old) by ventilation with 8% O2 in nitrogen. When systolic blood pressure had fallen to 20 mm Hg, animals were randomly reoxygenated with either 21% O2...

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