Iontophoretic study of speed of action of various muscle relaxants

The speed of action of nondepolarizing muscle relaxants is inversely related to potency. The hypothesis that this effect occurs at the end plate was tested in a frog (Rana pipiens) cutaneous pectoris muscle preparation. Brief acetylcholine pulses (10-100 ms) were applied iontophoretically from a cen...

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Veröffentlicht in:	Anesthesiology (Philadelphia) 1992-08, Vol.77 (2), p.351-356
Hauptverfasser:	LAW MIN, J. C, BEKAVAC, I, GLAVINOVIC, M. I, DONATI, F, BEVAN, D. R
Format:	Artikel
Sprache:	eng
Schlagworte:	Androstanols - pharmacology Anesthetics. Neuromuscular blocking agents Animals Atracurium - pharmacology Biological and medical sciences Gallamine Triethiodide - pharmacology Iontophoresis Isoquinolines - pharmacology Medical sciences Motor Endplate - drug effects Motor Endplate - physiology Neuromuscular Junction - drug effects Neuromuscular Junction - physiology Neuromuscular Nondepolarizing Agents - pharmacology Neuropharmacology Pancuronium - pharmacology Pharmacology. Drug treatments Rana pipiens Rocuronium Time Factors Tubocurarine - pharmacology Vecuronium Bromide - pharmacology
Online-Zugang:	Volltext
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