CD8 lymphocytosis and pseudotumoral splenomegaly in HIV infection

Three patients infected with human immunodeficiency virus (HIV) presented with pseudotumoral splenomegaly, CD8 lymphocytosis (3·5-5·1 × 10 9/l), and hypergammaglobulinaemia. Spleen and bone marrow showed diffuse CD8 lymphocyte and plasma-cell infiltration. Amplification of the T-cell-receptor gamma...

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Veröffentlicht in:	The Lancet (British edition) 1992-07, Vol.340 (8813), p.207-208
Hauptverfasser:	Oksenhendler, E., Seligmann, M., Clauvel, J-P., Gorochov, G., d'Agay, M.F., Autran, Brigitte
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Acquired Immunodeficiency Syndrome - complications Acquired Immunodeficiency Syndrome - immunology Adult AIDS AIDS/HIV Biological and medical sciences Bone marrow CD8 Antigens - immunology CD8 Antigens - isolation & purification Female Genetics Homosexuality Humans Immune response Immunity (Disease) Immunity, Cellular Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Lymphocytes Lymphocytosis - complications Lymphocytosis - immunology Male Medical research Medical sciences Opportunistic Infections - complications Opportunistic Infections - immunology Phenotype Splenomegaly - complications Viruses
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