Structural analysis and sheep pituitary receptor binding of GnRH and its complexes with metal ions

Binding of GnRH and its metal complexes to a sheep pituitary receptor have been investigated showing that Cu(II)–GnRH complex is more effectively bound to the receptor than the metal-free ligand, while Ni(II) and Co(II) complexes are less effective than the metal-free GnRH. Earlier studies have expl...

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Veröffentlicht in:	Journal of inorganic biochemistry 2003-02, Vol.94 (1), p.28-35
Hauptverfasser:	D’Amelio, Nicola, Gaggelli, Elena, Gajewska, Alina, Kochman, Helena, Kochman, Kazimierz, Kozlowski, Henryk, Latajka, Zdzislaw, Mlynarz, Piotr, Panek, Jaroslaw, Valensin, Gianni
Format:	Artikel
Sprache:	eng
Schlagworte:	1H NMR Animals GnRH Gonadotropin-Releasing Hormone - metabolism Metal complexes Metals - metabolism Nuclear Magnetic Resonance, Biomolecular Pituitary Gland - metabolism Protein Binding Receptors, LHRH - metabolism Sheep Sheep pituitary receptor binding
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