Myosin Va facilitates the distribution of secretory granules in the F-actin rich cortex of PC12 cells

Neuroendocrine secretory granules, the storage organelles for neuropeptides and hormones, are formed at the trans-Golgi network, stored inside the cell and exocytosed upon stimulation. Previously, we have reported that newly formed secretory granules of PC12 cells are transported in a microtubule-de...

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Veröffentlicht in:	Journal of cell science 2003-04, Vol.116 (Pt 7), p.1339-1348
Hauptverfasser:	Rudolf, Rüdiger, Kögel, Tanja, Kuznetsov, Sergei A, Salm, Thorsten, Schlicker, Oliver, Hellwig, Andrea, Hammer, 3rd, John A, Gerdes, Hans-Hermann
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism Actins - ultrastructure Animals Cell Compartmentation - physiology Cytoplasm - metabolism Cytoplasm - ultrastructure Cytoskeleton - metabolism Cytoskeleton - ultrastructure Microscopy, Electron Microtubules - metabolism Microtubules - ultrastructure Myosin Heavy Chains - genetics Myosin Heavy Chains - metabolism Myosin Heavy Chains - ultrastructure Myosin Type V - genetics Myosin Type V - metabolism Myosin Type V - ultrastructure PC12 Cells Protein Structure, Tertiary - physiology Protein Transport - physiology Rats Secretory Vesicles - metabolism Secretory Vesicles - ultrastructure
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