Down to the origin: Cdc6 protein and the competence to replicate

In eukaryotes, DNA replication requires the regulated assembly of pre-replicative complexes (pre-RCs) onto DNA during G1 phase. Pre-RCs render the chromatin competent to replicate, yet it is only at the G1–S phase transition that protein-kinase complexes trigger the transition to DNA replication. Ce...

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Veröffentlicht in:	Trends in cell biology 2003-03, Vol.13 (3), p.110-113
1. Verfasser:	Pelizon, Cristina
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Cycle Proteins - genetics Cell Cycle Proteins - metabolism Cell Differentiation - genetics Cell Division - genetics DNA Replication - genetics DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Eukaryotic Cells - metabolism Macromolecular Substances Meiosis - genetics Saccharomyces cerevisiae Proteins
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