Matrix metalloproteinases (MMPs) in bladder cancer: the induction of MMP9 by epidermal growth factor and its detection in urine

OBJECTIVES To investigate the matrix metalloproteinases (MMPs) 2 and 9 in bladder cancer cell lines stimulated with epidermal growth factor (EGF), and to investigate the presence of gelatinases in the urine of patients with bladder tumours, in relation to the stage and grade of tumour and the EGF re...

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Veröffentlicht in:	BJU international 2003-01, Vol.91 (1), p.99-104
Hauptverfasser:	Nutt, J.E., Durkan, G.C., Mellon, J.K., Lunec, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences bladder cancer Blotting, Western epidermal growth factor Epidermal Growth Factor - physiology human bladder cell lines Humans Matrix Metalloproteinase 2 - metabolism Matrix Metalloproteinase 2 - urine Matrix Metalloproteinase 9 - metabolism Matrix Metalloproteinase 9 - urine matrix metalloproteinases (MMP) Matrix Metalloproteinases - metabolism Medical sciences Neoplasm Proteins - metabolism Nephrology. Urinary tract diseases Tumor Cells, Cultured Tumors of the urinary system Urinary Bladder Neoplasms - enzymology Urinary Bladder Neoplasms - urine Urinary tract. Prostate gland urine
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