Large-scale isolation of CD133+ progenitor cells from G-CSF mobilized peripheral blood stem cells

We have evaluated the feasibility of large-scale isolation of CD133+ progenitors from healthy mobilized adult donors for potential clinical use in autologous and allogeneic transplantation. A total of 11 healthy volunteer adult donors were mobilized with G-CSF. CD133+ stem cells were isolated from a...

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Veröffentlicht in:	Bone marrow transplantation (Basingstoke) 2003-01, Vol.31 (1), p.17-22
Hauptverfasser:	GORDON, P. R, LEIMIG, T, BABARIN-DORNER, A, HOUSTON, J, HOLLADAY, M, MUELLER, I, GEIGER, T, HANDGRETINGER, R
Format:	Artikel
Sprache:	eng
Schlagworte:	AC133 Antigen Adult Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Antigens, CD - blood Biological and medical sciences Bone marrow Bone marrow, stem cells transplantation. Graft versus host reaction Cell Separation Colony-Forming Units Assay Complications and side effects Development and progression DNA Primers Filgrastim Flow Cytometry Glycoproteins - blood Graft versus host reaction Granulocyte colony-stimulating factor Granulocyte Colony-Stimulating Factor - therapeutic use Hematopoietic Stem Cell Mobilization - methods Hematopoietic stem cells Hematopoietic Stem Cells - cytology Hematopoietic Stem Cells - immunology Humans Leukapheresis Living Donors Medical sciences Mice Mice, Inbred NOD Mice, SCID Peptides - blood Physiological aspects Polymerase Chain Reaction - methods Prevention Recombinant Proteins Stem cell transplantation Transfusions. Complications. Transfusion reactions. Cell and gene therapy Transplantation Transplantation, Heterologous
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