An immunomodulatory protein, ling ZHI-8, facilitates cellular interaction through modulation of adhesion molecules

Ling Zhi-8 (LZ-8), a novel immunomodulatory protein, markedly enhanced the expression of CDllb, but not CDlla, CD13, CD14, CD18, CD33 or HLA-DR, on the U937 cell line in a dose-dependent fashion. It also induced ICAM-1 expression on vascular endothelial cells and significantly augmented γ -interfero...

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Veröffentlicht in:	Biochemical and biophysical research communications 1992-07, Vol.186 (1), p.385-390
Hauptverfasser:	Miyasaka, Nobuyuki, Inoue, Hiroko, Totsuka, Tetsuya, Koike, Ryuji, Kino, Kohsuke, Tsunoo, Hajime
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic - pharmacology Antibodies, Monoclonal Antigens, CD - analysis Antigens, CD - metabolism Biological and medical sciences Cell Adhesion Molecules - biosynthesis Cell Adhesion Molecules - metabolism Cell interactions, adhesion Cell Line Cells, Cultured Endothelium, Vascular - drug effects Endothelium, Vascular - physiology Enzyme-Linked Immunosorbent Assay Fundamental and applied biological sciences. Psychology Fungal Proteins - pharmacology HLA-DR Antigens - metabolism Humans Intercellular Adhesion Molecule-1 Interferon-gamma - pharmacology Kinetics Molecular and cellular biology Recombinant Proteins Umbilical Veins
Online-Zugang:	Volltext
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