Differences in neuroanatomical sites of apoD elevation discriminate between schizophrenia and bipolar disorder

We previously demonstrated that apolipoprotein D (apoD) levels are elevated in the dorsolateral prefrontal cortex and caudate obtained postmortem from subjects with schizophrenia and bipolar disorder compared to controls, suggesting a focal compensatory response to neuropathology associated with psy...

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Veröffentlicht in:	Molecular psychiatry 2003-02, Vol.8 (2), p.167-175
Hauptverfasser:	Thomas, E A, Dean, B, Scarr, E, Copolov, D, Sutcliffe, J G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adult and adolescent clinical studies Amygdala Amygdala - metabolism Amygdala - pathology Anatomy Apolipoproteins Autopsy Behavioral Sciences Biological and medical sciences Biological Psychology Bipolar disorder Bipolar Disorder - metabolism Bipolar Disorder - pathology Bipolar disorders Brain Brain - metabolism Brain - pathology Brain architecture Brain research Brodmann's area Cortex (cingulate) Cortex (parietal) Diagnosis, Differential Disease Enzyme-linked immunosorbent assay Female Gyrus Cinguli - metabolism Gyrus Cinguli - pathology Humans immediate-communication Ligands Male Medical sciences Medicine Medicine & Public Health Mental disorders Middle Aged Molecular biology Mood disorders Neurosciences Parietal Lobe - metabolism Parietal Lobe - pathology Pathology Pharmacotherapy Physiology Prefrontal cortex Prefrontal Cortex - metabolism Prefrontal Cortex - pathology Proteins Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Research centers Schizophrenia Schizophrenia - metabolism Schizophrenia - pathology T-Box Domain Proteins - metabolism Thalamus Thalamus - metabolism Thalamus - pathology Tropical medicine Xenopus Proteins
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