Optimizing the detection of bidirectional block across the flutter isthmus for patients with typical isthmus-dependent atrial flutter
The purpose of this study was to show that multipolar electrographic recordings along the subeustachian isthmus (SI) can better differentiate slow conduction from complete isthmus block after atrial flutter ablation, leading to a lower incidence of recurrent atrial flutter (Afl). Despite the presenc...
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Veröffentlicht in: | The American journal of cardiology 2003-03, Vol.91 (5), p.559-564 |
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description | The purpose of this study was to show that multipolar electrographic recordings along the subeustachian isthmus (SI) can better differentiate slow conduction from complete isthmus block after atrial flutter ablation, leading to a lower incidence of recurrent atrial flutter (Afl). Despite the presence of various techniques to identify bidirectional conduction block (BDB) after isthmus ablation for typical Afl, several studies, including a report from a national registry, suggest that radiofrequency ablation is still associated with a 15% recurrence rate. Thus, techniques that can distinguish slow conduction from complete isthmus block have the potential for reducing long-term recurrences. We evaluated patients who underwent radiofrequency ablation for typical isthmus-dependent Afl. Patients were separated into 2 groups. Group A underwent assessment of BDB with conventional methods. In group B, BDB was assessed by placing a multipolar catheter along the floor of the SI, pacing adjacent to the line of radiofrequency application, and assessing electrographic activation on either side. One hundred thirty-one cases of Afl ablation were analyzed (86 in group A, 45 in group B). Over a mean follow-up period of 17 months, recurrence rates of Afl were 16.5% in group A and 4.3% in group B (p = 0.043). Thus, assessment of BDB by placement of a multipolar catheter across the SI after ablation of typical Afl is associated with a significant reduction in long-term recurrence of Afl. |
doi_str_mv | 10.1016/S0002-9149(02)03306-4 |
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Despite the presence of various techniques to identify bidirectional conduction block (BDB) after isthmus ablation for typical Afl, several studies, including a report from a national registry, suggest that radiofrequency ablation is still associated with a 15% recurrence rate. Thus, techniques that can distinguish slow conduction from complete isthmus block have the potential for reducing long-term recurrences. We evaluated patients who underwent radiofrequency ablation for typical isthmus-dependent Afl. Patients were separated into 2 groups. Group A underwent assessment of BDB with conventional methods. In group B, BDB was assessed by placing a multipolar catheter along the floor of the SI, pacing adjacent to the line of radiofrequency application, and assessing electrographic activation on either side. One hundred thirty-one cases of Afl ablation were analyzed (86 in group A, 45 in group B). Over a mean follow-up period of 17 months, recurrence rates of Afl were 16.5% in group A and 4.3% in group B (p = 0.043). Thus, assessment of BDB by placement of a multipolar catheter across the SI after ablation of typical Afl is associated with a significant reduction in long-term recurrence of Afl.</description><identifier>ISSN: 0002-9149</identifier><identifier>EISSN: 1879-1913</identifier><identifier>DOI: 10.1016/S0002-9149(02)03306-4</identifier><identifier>PMID: 12615260</identifier><identifier>CODEN: AJCDAG</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Aged ; Atrial Flutter - diagnosis ; Atrial Flutter - mortality ; Atrial Flutter - surgery ; Biological and medical sciences ; Cardiac Catheterization - methods ; Cardiac dysrhythmias ; Cardiology. Vascular system ; Cardiovascular disease ; Catheter Ablation - methods ; Cohort Studies ; Electrocardiography - methods ; Electrophysiologic Techniques, Cardiac - methods ; Female ; Follow-Up Studies ; Heart ; Heart Atria - physiopathology ; Heart Conduction System - physiopathology ; Humans ; Male ; Medical sciences ; Middle Aged ; Patients ; Probability ; Prospective Studies ; Recurrence ; Risk Assessment ; Sensitivity and Specificity ; Severity of Illness Index ; Statistics, Nonparametric ; Treatment Outcome</subject><ispartof>The American journal of cardiology, 2003-03, Vol.91 (5), p.559-564</ispartof><rights>2003 Excerpta Medica Inc.</rights><rights>2003 INIST-CNRS</rights><rights>Copyright Elsevier Sequoia S.A. 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Despite the presence of various techniques to identify bidirectional conduction block (BDB) after isthmus ablation for typical Afl, several studies, including a report from a national registry, suggest that radiofrequency ablation is still associated with a 15% recurrence rate. Thus, techniques that can distinguish slow conduction from complete isthmus block have the potential for reducing long-term recurrences. We evaluated patients who underwent radiofrequency ablation for typical isthmus-dependent Afl. Patients were separated into 2 groups. Group A underwent assessment of BDB with conventional methods. In group B, BDB was assessed by placing a multipolar catheter along the floor of the SI, pacing adjacent to the line of radiofrequency application, and assessing electrographic activation on either side. One hundred thirty-one cases of Afl ablation were analyzed (86 in group A, 45 in group B). Over a mean follow-up period of 17 months, recurrence rates of Afl were 16.5% in group A and 4.3% in group B (p = 0.043). Thus, assessment of BDB by placement of a multipolar catheter across the SI after ablation of typical Afl is associated with a significant reduction in long-term recurrence of Afl.</description><subject>Aged</subject><subject>Atrial Flutter - diagnosis</subject><subject>Atrial Flutter - mortality</subject><subject>Atrial Flutter - surgery</subject><subject>Biological and medical sciences</subject><subject>Cardiac Catheterization - methods</subject><subject>Cardiac dysrhythmias</subject><subject>Cardiology. Vascular system</subject><subject>Cardiovascular disease</subject><subject>Catheter Ablation - methods</subject><subject>Cohort Studies</subject><subject>Electrocardiography - methods</subject><subject>Electrophysiologic Techniques, Cardiac - methods</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Heart</subject><subject>Heart Atria - physiopathology</subject><subject>Heart Conduction System - physiopathology</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Patients</subject><subject>Probability</subject><subject>Prospective Studies</subject><subject>Recurrence</subject><subject>Risk Assessment</subject><subject>Sensitivity and Specificity</subject><subject>Severity of Illness Index</subject><subject>Statistics, Nonparametric</subject><subject>Treatment Outcome</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc2L1TAUxYMozpvRP0EJgqKLar7aNKtBhvEDBmahrkOa3vgytk1NUmXc-3-b91occOPqcrm_c7icg9ATSl5TQps3nwghrFJUqJeEvSKck6YS99COtlJVVFF-H-3-IifoNKWbslJaNw_RCWUNrVlDduj39Zz96H_56SvOe8A9ZLDZhwkHhzvf-7iuZsDdEOw3bGwMKR1ZNyw5Q8Q-5f24JOxCxLPJHqac8E-f9zjfzt4W6UZUPcww9eWOTY6-HDaLR-iBM0OCx9s8Q1_eXX6--FBdXb__ePH2qrKCtrmyqhO9EMRyzjtDJSPKKKa45LJ2DISTClqjKJGO8Q6IBGNEp2reK0Goa_gZerH6zjF8XyBlPfpkYRjMBGFJWpYU25azAj77B7wJSywpJM044ZK19QGqV-gYSQSn5-hHE281JfpQkj6WpA8N6DKPJWlRdE8386Ubob9Tba0U4PkGmFTic9FM1qc7TjQ1o7Us3PnKQcnsh4eoky3pW1hr033w_3nlD0AgsA0</recordid><startdate>20030301</startdate><enddate>20030301</enddate><creator>Mangat, Iqwal</creator><creator>Yang, Yanfei</creator><creator>Cheng, Jie</creator><creator>Keung, Edmund C</creator><creator>Scheinman, Melvin M</creator><general>Elsevier Inc</general><general>Elsevier</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TS</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>M7Z</scope><scope>NAPCQ</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20030301</creationdate><title>Optimizing the detection of bidirectional block across the flutter isthmus for patients with typical isthmus-dependent atrial flutter</title><author>Mangat, Iqwal ; Yang, Yanfei ; Cheng, Jie ; Keung, Edmund C ; Scheinman, Melvin M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c418t-c9b4d440c333ba17209a92937375f2e4f79e8a9107f23be07eaa4b953d9401f63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Aged</topic><topic>Atrial Flutter - diagnosis</topic><topic>Atrial Flutter - mortality</topic><topic>Atrial Flutter - surgery</topic><topic>Biological and medical sciences</topic><topic>Cardiac Catheterization - methods</topic><topic>Cardiac dysrhythmias</topic><topic>Cardiology. Vascular system</topic><topic>Cardiovascular disease</topic><topic>Catheter Ablation - methods</topic><topic>Cohort Studies</topic><topic>Electrocardiography - methods</topic><topic>Electrophysiologic Techniques, Cardiac - methods</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Heart</topic><topic>Heart Atria - physiopathology</topic><topic>Heart Conduction System - physiopathology</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Patients</topic><topic>Probability</topic><topic>Prospective Studies</topic><topic>Recurrence</topic><topic>Risk Assessment</topic><topic>Sensitivity and Specificity</topic><topic>Severity of Illness Index</topic><topic>Statistics, Nonparametric</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mangat, Iqwal</creatorcontrib><creatorcontrib>Yang, Yanfei</creatorcontrib><creatorcontrib>Cheng, Jie</creatorcontrib><creatorcontrib>Keung, Edmund C</creatorcontrib><creatorcontrib>Scheinman, Melvin M</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Physical Education Index</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biochemistry Abstracts 1</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mangat, Iqwal</au><au>Yang, Yanfei</au><au>Cheng, Jie</au><au>Keung, Edmund C</au><au>Scheinman, Melvin M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Optimizing the detection of bidirectional block across the flutter isthmus for patients with typical isthmus-dependent atrial flutter</atitle><jtitle>The American journal of cardiology</jtitle><addtitle>Am J Cardiol</addtitle><date>2003-03-01</date><risdate>2003</risdate><volume>91</volume><issue>5</issue><spage>559</spage><epage>564</epage><pages>559-564</pages><issn>0002-9149</issn><eissn>1879-1913</eissn><coden>AJCDAG</coden><abstract>The purpose of this study was to show that multipolar electrographic recordings along the subeustachian isthmus (SI) can better differentiate slow conduction from complete isthmus block after atrial flutter ablation, leading to a lower incidence of recurrent atrial flutter (Afl). Despite the presence of various techniques to identify bidirectional conduction block (BDB) after isthmus ablation for typical Afl, several studies, including a report from a national registry, suggest that radiofrequency ablation is still associated with a 15% recurrence rate. Thus, techniques that can distinguish slow conduction from complete isthmus block have the potential for reducing long-term recurrences. We evaluated patients who underwent radiofrequency ablation for typical isthmus-dependent Afl. Patients were separated into 2 groups. Group A underwent assessment of BDB with conventional methods. In group B, BDB was assessed by placing a multipolar catheter along the floor of the SI, pacing adjacent to the line of radiofrequency application, and assessing electrographic activation on either side. One hundred thirty-one cases of Afl ablation were analyzed (86 in group A, 45 in group B). Over a mean follow-up period of 17 months, recurrence rates of Afl were 16.5% in group A and 4.3% in group B (p = 0.043). Thus, assessment of BDB by placement of a multipolar catheter across the SI after ablation of typical Afl is associated with a significant reduction in long-term recurrence of Afl.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>12615260</pmid><doi>10.1016/S0002-9149(02)03306-4</doi><tpages>6</tpages></addata></record> |
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subjects | Aged Atrial Flutter - diagnosis Atrial Flutter - mortality Atrial Flutter - surgery Biological and medical sciences Cardiac Catheterization - methods Cardiac dysrhythmias Cardiology. Vascular system Cardiovascular disease Catheter Ablation - methods Cohort Studies Electrocardiography - methods Electrophysiologic Techniques, Cardiac - methods Female Follow-Up Studies Heart Heart Atria - physiopathology Heart Conduction System - physiopathology Humans Male Medical sciences Middle Aged Patients Probability Prospective Studies Recurrence Risk Assessment Sensitivity and Specificity Severity of Illness Index Statistics, Nonparametric Treatment Outcome |
title | Optimizing the detection of bidirectional block across the flutter isthmus for patients with typical isthmus-dependent atrial flutter |
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