Insulin-like growth factor-I inhibits apoptosis in IL-3-dependent hemopoietic cells

The death of hemopoietic cells on withdrawal of CSF occurs by a mechanism known as apoptosis characterized by the early degradation of chromatin into oligonucleosome-length fragments. Insulin-like growth factor I plays a pivotal role in the regulation of somatic cell growth as a mediator of growth h...

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Veröffentlicht in:	The Journal of immunology (1950) 1992-07, Vol.149 (2), p.535-540
Hauptverfasser:	Rodriguez-Tarduchy, G, Collins, MK, Garcia, I, Lopez-Rivas, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Ageing, cell death Animals Biological and medical sciences Cell physiology Cell Survival - drug effects Cells, Cultured DNA - biosynthesis Fundamental and applied biological sciences. Psychology Hematopoietic Stem Cells - drug effects Hematopoietic Stem Cells - physiology Insulin-Like Growth Factor I - pharmacology Interleukin-3 - physiology Mice Molecular and cellular biology
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