The effect of intravenous pamidronate on bone mineral density, bone histomorphometry, and parameters of bone turnover in adults with type IA osteogenesis imperfecta

The type IA osteogenesis imperfecta (OI) phenotype is characterized by multiple fractures, blue sclerae, and minimal skeletal deformity without dentinogenesis imperfecta. The object of this study was to determine the effect of treatment with intravenous pamidronate (30 mg) every 3 months on bone den...

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Veröffentlicht in:	Calcified tissue international 2003-02, Vol.72 (2), p.103-112
Hauptverfasser:	Shapiro, J R, McCarthy, E F, Rossiter, K, Ernest, K, Gelman, R, Fedarko, N, Santiago, H T, Bober, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Bone and Bones - drug effects Bone and Bones - pathology Bone Density - drug effects Bone Remodeling - drug effects Diphosphonates - administration & dosage Diphosphonates - blood Diphosphonates - therapeutic use Female Humans Infusions, Intravenous Male Middle Aged Osteogenesis Imperfecta - diagnosis Osteogenesis Imperfecta - drug therapy Osteogenesis Imperfecta - pathology Space life sciences
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