A reversible radioligand specific for the ETB receptor : [125I]Tyr13-Suc-[Glu9,Ala11,15]-endothelin-1(8-21), [125I]IRL 1620

Suc-[Glu9,Ala11,15]-endothelin(ET)-1(8-21), IRL 1620, is a linear ET-analog specific for the ET-isopeptide-nonselective ETB receptor. The radio-iodinated analog, [125I]IRL 1620, showed a single class of saturable binding to the ETB receptors in porcine lung membranes with a Kd of 18 pM and a Bmax of...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemical and biophysical research communications 1992-06, Vol.185 (3), p.867-873
Hauptverfasser:	WATAKABE, T, URADE, Y, TAKAI, M, UMEMURA, I, OKADA, T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding, Competitive Biological and medical sciences Cell Membrane - metabolism Cell receptors Cell structures and functions Endothelins - metabolism Fundamental and applied biological sciences. Psychology Hormone receptors. Growth factor receptors. Cytokine receptors. Prostaglandin receptors Iodine Radioisotopes Kinetics Lung - metabolism Molecular and cellular biology Peptide Fragments - metabolism Radioligand Assay Receptors, Cell Surface - metabolism Receptors, Endothelin Swine
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!