Abnormalities in Amino Acid Neurotransmitters in Discrete Brain Regions of Genetically Dystonic Hamsters

: The concentrations of 11 amino acids, including the neurotransmitters γ‐aminobutync acid, glutamate, aspartate, glycine, and taurine, were determined by HPLC in 12 brain regions of genetically dystonic (dtsz) hamsters and age‐matched nondystonic controls. Since dystonia in mutant dtsz hamsters is...

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Veröffentlicht in:	Journal of neurochemistry 1992-08, Vol.59 (2), p.689-694
Hauptverfasser:	Loescher, W, Hoerstermann, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Animals Aspartic Acid - analysis Aspartic Acid - metabolism Biological and medical sciences Cerebellum - chemistry Cerebellum - metabolism Chromatography, High Pressure Liquid Corpus Striatum - chemistry Corpus Striatum - metabolism Cricetinae - genetics Dystonia Dystonia - genetics Dystonia - metabolism gamma-Aminobutyric Acid - analysis gamma-Aminobutyric Acid - metabolism Glutamate Glutamates - analysis Glutamates - metabolism Glycine - analysis Glycine - metabolism Hamsters Medical sciences Nervous system (semeiology, syndromes) Nervous system as a whole Neurology Neurotransmitter Agents - analysis Neurotransmitter Agents - metabolism Striatum Taurine - analysis Taurine - metabolism Thalamus Thalamus - chemistry Thalamus - metabolism γ‐Aminobutyric acid
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