Mapping cortical change across the human life span

We used magnetic resonance imaging and cortical matching algorithms to map gray matter density (GMD) in 176 normal individuals ranging in age from 7 to 87 years. We found a significant, nonlinear decline in GMD with age, which was most rapid between 7 and about 60 years, over dorsal frontal and pari...

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Veröffentlicht in:	Nature neuroscience 2003-03, Vol.6 (3), p.309-315
Hauptverfasser:	Sowell, Elizabeth R, Peterson, Bradley S, Thompson, Paul M, Welcome, Suzanne E, Henkenius, Amy L, Toga, Arthur W
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Age Distribution Aged Aged, 80 and over Aging Animal Genetics and Genomics Behavioral Sciences Biological Techniques Biomedical and Life Sciences Biomedicine Brain Brain Mapping - methods Cerebral Cortex - anatomy & histology Cerebrospinal Fluid Child Cross-Sectional Studies Female Humans Image Processing, Computer-Assisted Magnetic Resonance Imaging Male Medical examination Middle Aged Neurobiology Neurosciences Physiological aspects Reference Values
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