L-glutamate and acetylcholine mobilise Ca2+ from the same intracellular pool in cerebellar granule cells using transduction mechanisms with different Ca2+ sensitivities

Ca2+ mobilisation induced by L-glutamate (Glu) and acetylcholine (ACh) has been studied in cultured cerebellar granule cells using digital fluorescence microscopy. The ability of Glu-receptor activation to mobilise Ca2+ was decreased when [Ca2+]o was lowered to 10 microM (from 1.8 mM). It was enhanc...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cell calcium (Edinburgh) 1992-05, Vol.13 (5), p.293-301
Hauptverfasser:	Irving, A J, Collingridge, G L, Schofield, J G
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine - physiology Animals Calcium - metabolism Cerebellar Cortex - drug effects Cerebellar Cortex - metabolism Cycloleucine - analogs & derivatives Cycloleucine - pharmacology Glutamates - physiology Pertussis Toxin Rats Receptors, Glutamate Receptors, Muscarinic - drug effects Receptors, Muscarinic - metabolism Receptors, Neurotransmitter - drug effects Receptors, Neurotransmitter - physiology Signal Transduction - drug effects Signal Transduction - physiology Virulence Factors, Bordetella - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!