Induction of myogenic differentiation by an expression vector encoding the DNA methyltransferase cDNA sequence in the antisense orientation

To test the hypothesis that DNA methylation controls the state of differentiation of a mammalian cell, we transfected the stable mesenchymal line 10T1/2 with an expression vector encoding sequences from the DNA methyltransferase (DNA MeTase) cDNA in the antisense orientation. 10T1/2 cells transfecte...

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Veröffentlicht in:	The Journal of biological chemistry 1992-06, Vol.267 (18), p.12831-12836
Hauptverfasser:	Szyf, M, Rouleau, J, Theberge, J, Bozovic, V
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Differentiation - genetics Cell Line Cloning, Molecular DNA Modification Methylases - genetics DNA Modification Methylases - metabolism DNA, Antisense Gene Expression Regulation Humans Kinetics Methylation Mice Restriction Mapping Transfection
Online-Zugang:	Volltext
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