Remodeling of the actin cytoskeleton during mammalian sperm capacitation and acrosome reaction

The sperm acrosome reaction and penetration of the egg follow zona pellucida binding only if the sperm has previously undergone the poorly understood maturation process known as capacitation. We demonstrate here that in vitro capacitation of bull, ram, mouse, and human sperm was accompanied by a tim...

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Veröffentlicht in:	Biology of reproduction 2003-03, Vol.68 (3), p.837-845
Hauptverfasser:	Brener, E, Rubinstein, S, Cohen, G, Shternall, K, Rivlin, J, Breibart, H
Format:	Artikel
Sprache:	eng
Schlagworte:	acrosome reaction Acrosome Reaction - physiology actin actin remodeling Actins - physiology Animals Biological and medical sciences bulls Calcimycin - pharmacology Calcium - antagonists & inhibitors Calcium - physiology capacitation Cattle cytochalasin D cytoskeleton Cytoskeleton - physiology depolymerization enzyme inhibitors Female Fertilization in Vitro Fundamental and applied biological sciences. Psychology Humans Immunoblotting in vitro fertilization Ionophores - pharmacology Male Mammalian male genital system Mice Mice, Inbred BALB C Microscopy, Fluorescence Morphology. Physiology polymerization protein phosphorylation rams Sheep Sperm Capacitation - physiology Sperm-Ovum Interactions - physiology spermatozoa Spermatozoa - physiology tyrosine tyrosine phosphorylation Vertebrates: reproduction
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