Cutting Edge: Molecular Cloning of a Killer Cell Ig-Like Receptor in the Mouse and Rat

We report the molecular cloning of a KIR3DL1 receptor in the mouse and the rat, between 37.4 and 45.4% identical with primate killer cell Ig-like receptors (KIRs/CD158). Both mouse and rat molecules contain a pair of immunoreceptor tyrosine-based inhibition motifs in their cytoplasmic regions, sugge...

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Veröffentlicht in:	The Journal of immunology (1950) 2003-03, Vol.170 (5), p.2259-2263
Hauptverfasser:	Hoelsbrekken, Sigurd E, Nylenna, Oyvind, Saether, Per C, Slettedal, Imer O, Ryan, James C, Fossum, Sigbjorn, Dissen, Erik
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Cell Line Chromosome Mapping Cloning, Molecular Cricetinae DNA, Complementary - isolation & purification Humans Killer Cells, Natural - immunology Killer Cells, Natural - metabolism Membrane Proteins - biosynthesis Membrane Proteins - genetics Mice Mice, Inbred BALB C Mice, Inbred C57BL Molecular Sequence Data Rats Receptors, Immunologic - biosynthesis Receptors, Immunologic - chemistry Receptors, Immunologic - genetics Receptors, KIR Receptors, KIR3DL1 Sequence Homology, Amino Acid Transcription, Genetic - immunology Transfection
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