Indomethacin reduces lipid peroxidation in rat brain homogenate by binding Fe2

One of the hallmarks of Alzheimer's disease (AD) is the progressive degeneration of cholinergic neurons in the cerebral cortex and hippocampus. It is generally accepted that this neuronal degeneration is due to free-radical-induced damage. These free radicals attack vital structural components...

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Veröffentlicht in:	Metabolic brain disease 2003-03, Vol.18 (1), p.1-9
Hauptverfasser:	ANOOPKUMAR-DUKIE, Shailendra, LACK, Barbara, MCPHAIL, Kerry, NYOKONG, Tebello, LAMBAT, Zaynab, MAHARAJ, Deepa, DAYA, Santy
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents, Non-Steroidal - metabolism Anti-Inflammatory Agents, Non-Steroidal - pharmacology Biological and medical sciences Brain - metabolism Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Indomethacin - metabolism Indomethacin - pharmacology Iron - metabolism Lipid Peroxidation - drug effects Magnetic Resonance Spectroscopy Male Medical sciences Neurology Neuropharmacology Neuroprotective agent Neuroprotective Agents - metabolism Neuroprotective Agents - pharmacology Pharmacology. Drug treatments Rats Rats, Wistar Spectrophotometry
Online-Zugang:	Volltext
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