Loss of expression of the DCC gene during progression of colorectal carcinomas in familial adenomatous polyposis and non-familial adenomatous polyposis patients

We have previously observed that the frequency of loss of heterozygosity (LOH) on chromosome 18q was low in adenomas and intramucosal carcinomas, whereas invasive carcinomas exhibited a high frequency in familial adenomatous polyposis patients (M. Miyaki et al., Cancer Res., 50: 7166-7173, 1990). In...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1992-07, Vol.52 (13), p.3801-3803
Hauptverfasser:	KIKUCHI-YANOSHITA, R, KONISHI, M, FUKUNARI, H, TANAKA, K, MIYAKI, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoma - genetics Adenomatous Polyposis Coli - genetics Base Sequence Biological and medical sciences Carcinoma - genetics Chromosome Deletion Chromosomes, Human, Pair 18 Colonic Polyps - genetics colorectal carcinoma Colorectal Neoplasms - genetics DCC gene expression Gastroenterology. Liver. Pancreas. Abdomen genes Heterozygote Humans man Medical sciences Molecular Sequence Data polyposis Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Tumors
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