Elevation of cytokine levels in cachectic patients with prostate carcinoma

BACKGROUND Approximately 60–70% of patients with advanced prostate carcinoma (CaP) suffer from cachexia, one of the most devastating conditions associated with advanced malignant disease. The pathophysiology of cachexia is multifactorial, and several cytokines, such as tumor necrosis factor α (TNFα)...

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Veröffentlicht in:	Cancer 2003-03, Vol.97 (5), p.1211-1216
Hauptverfasser:	Pfitzenmaier, Jesco, Vessella, Robert, Higano, Celestia S., Noteboom, Jennifer L., Wallace, David, Corey, Eva
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences cachexia Cachexia - blood Cachexia - etiology cytokines Cytokines - blood Humans Interleukin-1 - blood Interleukin-6 - blood Interleukin-8 - blood interleukins Male Medical sciences Middle Aged Nephrology. Urinary tract diseases prostate specific antigen (PSA) Prostate-Specific Antigen - blood prostatic neoplasm Prostatic Neoplasms - blood Prostatic Neoplasms - complications Prostatic Neoplasms - radiotherapy Tumor Necrosis Factor-alpha - metabolism Tumors of the urinary system Urinary tract. Prostate gland
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