Fluoxetine shortens circadian period for wheel running activity in mice

Fluoxetine is a potent and specific serotonin re-uptake inhibitor and an effective antidepressant drug. Male mice were treated with either fluoxetine (8 mg/kg body weight per day) or saline. Wheel running activity was monitored for 2 weeks in a 12:12 LD cycle followed by 2 weeks in constant darkness...

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Veröffentlicht in:	Brain research bulletin 1992-04, Vol.28 (4), p.629-631
Hauptverfasser:	Possidente, Bernard, Lumia, Augustus R., McEldowney, Sara, Rapp, Mark
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Chronobiology Circadian period Circadian Rhythm - drug effects Fluoxetine Fluoxetine - pharmacology Fundamental and applied biological sciences. Psychology Injections, Intravenous Male Mice Motor Activity - drug effects Serotonin Serotonin - physiology Vertebrates: anatomy and physiology, studies on body, several organs or systems Wheel running activity
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