Remifentanil and nitrous oxide reduce changes in cerebral blood flow velocity in the middle cerebral artery caused by pain

Cerebral blood flow is affected by painful stimuli, and analgesic agents may alter the response of cerebral blood flow to pain. We set out to quantify the effects of remifentanil and nitrous oxide on blood flow changes caused by experimental pain. We simulated surgical pain in 10 conscious volunteer...

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Veröffentlicht in:	British journal of anaesthesia : BJA 2003-03, Vol.90 (3), p.296-299
Hauptverfasser:	Lorenz, I.H., Kolbitsch, C., Hinteregger, M., Bauer, P., Spiegel, M., Luger, T.J., Schmidauer, C., Streif, W., Pfeiffer, K.P., Benzer, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult anaesthetics gases anaesthetics gases, nitrous oxide Analgesics analgesics opioid analgesics opioid, remifentanil Analgesics, Non-Narcotic - therapeutic use Analgesics, Opioid - administration & dosage Analgesics, Opioid - therapeutic use Anesthetics, Inhalation - therapeutic use Biological and medical sciences blood flow Blood Flow Velocity - drug effects brain brain, blood flow Cerebrovascular Circulation - drug effects Humans Infusions, Parenteral Intraoperative Period Male Medical sciences Middle Cerebral Artery - diagnostic imaging Middle Cerebral Artery - physiopathology Neuropharmacology nitrous oxide Nitrous Oxide - therapeutic use pain Pain - diagnostic imaging Pain - drug therapy Pharmacology. Drug treatments Piperidines - administration & dosage Piperidines - therapeutic use Remifentanil Ultrasonography, Doppler, Transcranial - methods
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