Demonstration of TARC and CCR4 mRNA Expression and Distribution Using In situ RT‐PCR in the Lesional Skin of Atopic Dermatitis

Thymus‐ and activation‐regulated chemokine (TARC/CCL17) and its receptor, CC chemokine receptor 4 (CCR4), have been proven to be involved in a number of allergic diseases, especially atopic dermatitis (AD). The purpose of this study was to examine the expression and distribution of TARC and CCR4 mRN...

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Veröffentlicht in:	Journal of dermatology 2003-01, Vol.30 (1), p.26-32
Hauptverfasser:	Zheng, Xueyi, Nakamura, Koichiro, Furukawa, Hirotoshi, Nishibu, Akiko, Takahashi, Masabumi, Tojo, Michiko, Kaneko, Fumio, Kakinuma, Takashi, Tamaki, Kunihiko
Format:	Artikel
Sprache:	eng
Schlagworte:	AD: atopic dermatitis Case-Control Studies CCR4: CC chemokine receptor 4 Chemokine CCL17 Chemokines, CC - genetics Chemokines, CC - metabolism Dermatitis, Atopic - metabolism Dermatitis, Atopic - pathology DNA Primers Gene Expression Regulation Humans Receptors, CCR4 Receptors, Chemokine - genetics Receptors, Chemokine - metabolism Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - analysis Severity of Illness Index TARC: thymus‐ and activation‐regulated chemokine
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