Structure-activity relationship in the gastric cytoprotective effect of several sesquiterpene lactones
The structural requirements for the gastric cytoprotective activity of several sesquiterpene lactones are reported. A theoretical-experimental study on the potentially active centers is carried out. The biological evaluation of reduced analogues and the simulation of the molecular interactions betwe...
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Veröffentlicht in: | Journal of medicinal chemistry 1992-06, Vol.35 (13), p.2452-2458 |
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Hauptverfasser: | , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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