Linear acral pseudolymphomatous angiokeratoma of children (APACHE): Further evidence that APACHE is a cutaneous pseudolymphoma

Acral pseudolymphomatous angiokeratoma of children (APACHE) is a recently recognized, rare clinical entity. We report a case of APACHE in a 9-year-old Japanese girl with a dark red, linear plaque on the posterior area of the right lower leg. Histopathologic findings revealed further evidence that AP...

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Veröffentlicht in:Journal of the American Academy of Dermatology 2003-02, Vol.48 (2), p.S15-S17
Hauptverfasser: Kiyohara, Takahiro, Kumakiri, Masanobu, Kawasaki, Takeo, Takeuchi, Akiteru, Kuwahara, Hiroaki, Ueda, Takanori
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container_issue 2
container_start_page S15
container_title Journal of the American Academy of Dermatology
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creator Kiyohara, Takahiro
Kumakiri, Masanobu
Kawasaki, Takeo
Takeuchi, Akiteru
Kuwahara, Hiroaki
Ueda, Takanori
description Acral pseudolymphomatous angiokeratoma of children (APACHE) is a recently recognized, rare clinical entity. We report a case of APACHE in a 9-year-old Japanese girl with a dark red, linear plaque on the posterior area of the right lower leg. Histopathologic findings revealed further evidence that APACHE was a cutaneous pseudolymphoma rather than a vascular neoplasm because of the presence of distinct primary and secondary lymphoid follicles, and thick-walled, long blood vessels lined with prominent plump endothelial cells similar to high endothelial venules in the paracortical area of the lymph node. In addition to previous descriptions, the patient presented with a distinct linear lesion. Vacuolar alteration of the basal cell layer and scattered eosinophilic bodies in the epidermis were observed, which suggested a lichenoid tissue reaction. We believe that APACHE might show a distinct linear pattern accompanied by a lichenoid tissue reaction. (J Am Acad Dermatol 2003;48:S15-7.)
doi_str_mv 10.1067/mjd.2003.127
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source MEDLINE; ScienceDirect Journals (5 years ago - present)
subjects Angiokeratoma - immunology
Angiokeratoma - pathology
Biological and medical sciences
Child
Dermatology
Female
Humans
Medical sciences
Pseudolymphoma - immunology
Pseudolymphoma - pathology
Skin Diseases - immunology
Skin Diseases - pathology
Tumors of the skin and soft tissue. Premalignant lesions
title Linear acral pseudolymphomatous angiokeratoma of children (APACHE): Further evidence that APACHE is a cutaneous pseudolymphoma
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