Creation of an On-Chip Enzyme Reactor by Encapsulating Trypsin in Sol−Gel on a Plastic Microchip

Trypsin-encapsulated sol−gel was fabricated in situ onto a plastic microchip to form an on-chip bioreactor that integrates tryptic digestion, separation, and detection. Trypsin-encapsulated sol−gel, which is derived from alkoxysilane, was fabricated within a sample reservoir (SR) of the chip. Fluore...

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