Renoprotection by ACE Inhibition or Aldosterone Blockade Is Blood Pressure–Dependent

ABSTRACT—Renin-angiotensin-aldosterone system blockade has been shown to protect against renal damage in salt-supplemented, stroke-prone spontaneously hypertensive rats (SHRsp). Based on intermittent tail-cuff blood pressure (BP) measurements, it has been claimed that such protection is BP-independe...

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Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 2003-02, Vol.41 (2), p.201-206
Hauptverfasser:	Griffin, Karen A, Abu-Amarah, Isam, Picken, Maria, Bidani, Anil K
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin-Converting Enzyme Inhibitors - pharmacology Animals Antihypertensive agents Biological and medical sciences Blood Pressure - drug effects Blood Pressure - physiology Cardiovascular system Delayed-Action Preparations Enalapril - pharmacology Hypertension - physiopathology Hypertension - prevention & control Hypertension - urine Kidney - drug effects Kidney - pathology Linear Models Male Medical sciences Mineralocorticoid Receptor Antagonists - pharmacology Pharmacology. Drug treatments Proteinuria - urine Rats Rats, Inbred SHR Sodium Chloride - administration & dosage Spironolactone - pharmacology Time Factors
Online-Zugang:	Volltext
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