Retinal Changes in Otsuka Long-Evans Tokushima Fatty Rats (Spontaneously Diabetic Rat)—Possibility of a New Experimental Model for Diabetic Retinopathy

Purpose: To study retinal changes in the Otsuka Long-Evans Tokushima Fatty (OLETF) rat, a spontaneously diabetic rat, and evaluate it as a possible new diabetic retinopathy model. Methods: We examined the retinas of OLETF rats and Long-Evans Tokushima Otsuka (LETO) rats as controls under both a tran...

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Veröffentlicht in:	Japanese journal of ophthalmology 2003-01, Vol.47 (1), p.28-35
Hauptverfasser:	Lu, Zhong-Yang, Bhutto, Imran Ahmed, Amemiya, Tsugio
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Associated diseases and complications Biological and medical sciences Blood Glucose - analysis Body Weight Corrosion cast Corrosion Casting Diabetes. Impaired glucose tolerance diabetic retinopathy Diabetic Retinopathy - pathology Disease Models, Animal electron microscopy Endocrine pancreas. Apud cells (diseases) Endocrinopathies Hyperglycemia - pathology Male Medical sciences Microscopy, Electron, Scanning OLETF rat Ophthalmology Rats Rats, Inbred OLETF Rats, Long-Evans Retina - ultrastructure Retinal Vessels - ultrastructure Retinopathies spontaneously diabetic animal model
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