Total Synthesis of the Ramoplanin A2 and Ramoplanose Aglycon

Full details of a convergent total synthesis of the ramoplanin A2 and ramoplanose aglycon are disclosed. Three key subunits composed of residues 3−9 (heptapeptide 15), pentadepsipeptide 26 (residues 1, 2 and 15−17), and pentapeptide 34 (residues 10−14) were prepared, sequentially coupled, and cycliz...

Ausführliche Beschreibung