Disposition of short-chain aliphatic alcohols in rabbit vitreous by ocular microdialysis

Anatomic and physiological barriers limit drug delivery to the posterior segment of the eye via topical or systemic administration. Intravitreal administration has proven to be a safe and effective means of treating various posterior segment diseases. Elimination of a compound from the vitreous cham...

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Veröffentlicht in:	Experimental eye research 2003-03, Vol.76 (3), p.315-320
Hauptverfasser:	Atluri, Harisha, Mitra, Ashim K
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Propanol - pharmacokinetics alcohol Alcohols - pharmacokinetics Animals anterior chamber Biological and medical sciences blood retinal barrier Eye and associated structures. Visual pathways and centers. Vision Fundamental and applied biological sciences. Psychology Half-Life Heptanol - pharmacokinetics Injections, Intralesional lipophilicity Male Methanol - pharmacokinetics Microdialysis Pentanols - pharmacokinetics posterior segment Rabbits Vertebrates: nervous system and sense organs Vitreous Body - metabolism vitreous chamber vitreous disposition
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