α-Oxidation of 3-methyl-substituted fatty acids in rat liver

3-Methyl-substituted fatty acids are first oxidatively decarboxylated (α-oxidation) before they are degraded further via β-oxidation. We synthesized [1- 14C]phytanic and 3-[1- 14C]methylmargaric acids in order to study their α-oxidation in isolated rat hepatocytes, rat liver homogenates and subcellu...

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Veröffentlicht in:	Archives of biochemistry and biophysics 1992-07, Vol.296 (1), p.214-223
Hauptverfasser:	Huang, Shewen, Van Veldhoven, Paul P., Vanhoutte, Filip, Parmentier, Guido, Eyssen, Hendrik J., Mannaerts, Guy P.
Format:	Artikel
Sprache:	eng
Schlagworte:	3-methylmargaric acid Analytical, structural and metabolic biochemistry Animals Biological and medical sciences Buffers Carbon Radioisotopes Cells, Cultured Diphosphates - pharmacology Fatty acids Fatty Acids - chemical synthesis Fatty Acids - metabolism Free Radical Scavengers Fundamental and applied biological sciences. Psychology Kinetics Lipids liver Liver - metabolism Male Methylation Microsomes, Liver - metabolism Other biological molecules oxidation Oxidation-Reduction pathways phytanic acid Phytanic Acid - chemical synthesis Phytanic Acid - metabolism Radioisotope Dilution Technique Rats Rats, Inbred Strains Ribonucleotides - pharmacology Subcellular Fractions - metabolism Time Factors
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