Enhanced Synthesis of Cysteinyl Leukotrienes in Psoriasis

Cysteinyl leukotriene synthesis was investigated in patients with psoriasis. A non-invasive test requiring no stimulation was employed by measuring the major index metabolite of LTC4, which appears in urine. The presence of this metabolite, LTE4, was shown unequivocally by gas chromatography -- mass...

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Veröffentlicht in:	Journal of investigative dermatology 1992-07, Vol.99 (1), p.8-11
Hauptverfasser:	Fauler, Joachim, Neumann, Christine, Tsikas, Dimitrios, Frölich, Jürgen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Circadian Rhythm Creatinine Dermatology Female Gas chromatography Gas Chromatography-Mass Spectrometry High-performance liquid chromatography Humans Leukotriene E4 Leukotrienes Male Mass spectroscopy Medical sciences Metabolites Psoriasis Psoriasis - metabolism Psoriasis. Parapsoriasis. Lichen Radioimmunoassay SRS-A - analogs & derivatives SRS-A - biosynthesis SRS-A - urine Urine
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