Cytogenetic analysis in ataxia telangiectasia with malignant lymphoma

We present the results of cytogenetic analysis in a brother and sister with ataxia telangiectasia (AT), one of whom had malignant T-cell lymphoma. In both children, cytogenetic analysis of phytohemagglutinin (PHA)-stimulated lymphocytes showed chromosomal instability and inv(7) in 10% of the cells e...

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Veröffentlicht in:	Cancer genetics and cytogenetics 1992-06, Vol.60 (2), p.158-163
Hauptverfasser:	Petković, Iskra, Ligutić, Ivo, Dominis, Mara, Loffler-Badžak, Dagmar, Čepulić, Mladen, Nakić, Melita
Format:	Artikel
Sprache:	eng
Schlagworte:	ataxia telangiectasia Ataxia Telangiectasia - complications Ataxia Telangiectasia - genetics Ataxia Telangiectasia - pathology Biological and medical sciences Child chromosome 14 chromosome 7 Chromosome Aberrations Chromosome fragility (bloom syndrome, ataxia telangiectasia, fanconi anemia, x-linked mental retardation...) Chromosomes, Human, Pair 1 Chromosomes, Human, Pair 12 Chromosomes, Human, Pair 5 Female Humans inversion lymphocytes T lymphoma Lymphoma, T-Cell - complications Lymphoma, T-Cell - genetics Lymphoma, T-Cell - pathology Male man Medical genetics Medical sciences translocation Tumor Cells, Cultured
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