Kinetic Mechanism for the Formation of the Presynaptic Complex of the Bacterial Recombinase RecA

RecA protein from Escherichia colicatalyzes DNA strand exchange during homologous recombination in a reaction that requires nucleoside triphosphate cofactor. In the first step of this reaction RecA protein polymerizes on single-stranded DNA to form a filament with a stoichiometry of three nucleotide...

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Veröffentlicht in:The Journal of biological chemistry 2003-02, Vol.278 (6), p.3545-3551
Hauptverfasser: Defais, Martine, Phez, Emilie, Johnson, Neil P.
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Sprache:eng
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