Label-Free Chiral Detection of Melittin Binding to a Membrane

The study presented here describes an innovative approach for the detection of surface-confined proteins using chiral second harmonic generation (C-SHG). A unique optical geometry has been employed which allows for the separation of the chiral and achiral nonlinear response. By utilizing this optica...

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Veröffentlicht in:	Journal of the American Chemical Society 2003-02, Vol.125 (5), p.1148-1149
Hauptverfasser:	Kriech, Matthew A, Conboy, John C
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Aminoacids, peptides. Hormones. Neuropeptides Analytical, structural and metabolic biochemistry Biological and medical sciences Fundamental and applied biological sciences. Psychology Lipid Bilayers - chemistry Lipid Bilayers - metabolism Melitten - chemistry Melitten - metabolism Membranes - chemistry Membranes - metabolism Molecular Sequence Data Phosphatidylcholines - chemistry Phosphatidylcholines - metabolism Photons Protein Binding Protein Structure, Secondary Proteins Spectrum Analysis - methods Stereoisomerism
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