Safety and Immunogenicity of the Synthetic Malaria Vaccine SPf66 in a Large Field Trial

In the first field trial with synthetic malaria vaccine SPf66 in a large population naturally exposed to malaria, 9957 persons > 1 year old and residing on the Colombian Pacific coast received three doses of the vaccine. To evaluate vaccine safety, clinical observations were made 30 min and 48 h...

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Veröffentlicht in:	The Journal of infectious diseases 1992-07, Vol.166 (1), p.139-144
Hauptverfasser:	Amador, Roberto, Moreno, Alberto, Murillo, Luis Angel, Sierra, Oscar, Saavedra, David, Rojas, Mauricio, Mora, Ana Lucia, Rocha, Claudia Lucia, Alvarado, Fernando, Falla, Juan Carlos, Orozco, Mauricio, Coronell, Carlos, Ortega, Norella, Molano, Alberto, Velásquez, José Fernando, Valero, María Victoria, Franco, Lina, Guzmán, Fanny, Salazar, Luz Mary, Espejo, Fabiola, Mora, Elsa, Farfán, Rocío, Zapata, Nohora, Rosas, Jaiver, Calvo, Julio Cesar, Castro, Jaime, Quiñones, Teódulo, Nuñez, Francisco, Patarroyo, Manuel Elkin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Amino Acid Sequence Animals Antibodies Antibodies, Protozoan - biosynthesis Blood Pressure Blotting, Western Child Child, Preschool Dosage Enzyme-Linked Immunosorbent Assay Female Humans Immune response Immunization Immunoglobulin G - biosynthesis Infant Major Articles Malaria Malaria vaccine Malaria, Falciparum - prevention & control Male Molecular Sequence Data Parasites Plasmodium falciparum Plasmodium falciparum - immunology Polymers Protozoan Proteins - adverse effects Protozoan Proteins - chemistry Protozoan Proteins - immunology Protozoan Vaccines - adverse effects Protozoan Vaccines - chemistry Protozoan Vaccines - immunology Pruritus Recombinant Proteins Vaccination Vaccination - adverse effects
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