Synthesis and Turnover of Proteoglycans by Human and Bovine Adult Articular Chondrocytes Cultured in Alginate Beads

Human and bovine adult articular chondrocytes cultured in alginate beads or agarose gel retain their spherical shape and typical chondrocytic appearance for at least 5 weeks. Aggrecan is always the major population of proteoglycans (PGs) synthesized; its size varies depending upon the age of the car...

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Veröffentlicht in:	Matrix (Stuttgart) 1992-04, Vol.12 (2), p.116-129
Hauptverfasser:	Häuselmann, H.J., Aydelotte, M.B., Schumacher, B.L., Kuettner, K.E., Gitelis, S.H., Thonar, E. J.-M.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Aged aggrecan Aggrecans alginate beads Alginates Analytical, structural and metabolic biochemistry Animals Biological and medical sciences Cartilage, Articular - cytology Cartilage, Articular - metabolism Cattle Cell Division Cells, Cultured Culture Techniques - methods Extracellular Matrix - metabolism Extracellular Matrix Proteins Fundamental and applied biological sciences. Psychology Gels Glucuronic Acid Glycoproteins Hexuronic Acids human articular chondrocytes Humans Keratan Sulfate - metabolism Lectins, C-Type Male Microspheres Middle Aged Proteins proteoglycan-aggregates Proteoglycans - metabolism Sepharose
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