Expression of tumor necrosis factor-α in regenerating muscle fibers in inflammatory and non-inflammatory myopathies

The expression level of tumor necrosis factor (TNF)-alpha is elevated in idiopathic inflammatory myopathies and Duchenne muscular dystrophy (DMD), but the precise role of TNF-alpha is unknown. To elucidate the possible role of TNF-alpha, we investigated the expression of TNF-alpha and its receptor i...

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Veröffentlicht in:	Acta neuropathologica 2003-03, Vol.105 (3), p.217-224
Hauptverfasser:	KURU, Satoshi, INUKAI, Akira, KATO, Takashi, YIDENG LIANG, KIMURA, Seigo, SOBUE, Gen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Biological and medical sciences Child Child, Preschool Dermatomyositis - metabolism Dermatomyositis - pathology Diseases of striated muscles. Neuromuscular diseases Female Humans Immunohistochemistry In Situ Hybridization Male Medical sciences Middle Aged Muscle Fibers, Skeletal - pathology Muscle, Skeletal - pathology Muscle, Skeletal - physiology Muscular Diseases - metabolism Muscular Diseases - pathology Muscular Dystrophy, Duchenne - metabolism Muscular Dystrophy, Duchenne - pathology Myosin Heavy Chains - metabolism Neurology Polymyositis - metabolism Polymyositis - pathology Receptors, Tumor Necrosis Factor - biosynthesis Regeneration RNA, Messenger - analysis Tumor Necrosis Factor-alpha - biosynthesis
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