High prevalence of cobalamin deficiency in Guatemalan schoolchildren: associations with low plasma holotranscobalamin II and elevated serum methylmalonic acid and plasma homocysteine concentrations

Studies conducted in Guatemala, Mexico, and Venezuela have found high prevalences of low plasma cobalamin (vitamin B-12) concentrations in infants and children. It is not known whether these low cobalamin concentrations are accompanied by altered metabolic functions. We sought to assess the prevalen...

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Veröffentlicht in:	The American journal of clinical nutrition 2003-02, Vol.77 (2), p.433-440
Hauptverfasser:	ROGERS, Lisa M, BOY, Erick, MILLER, Joshua W, GREEN, Ralph, SABEL, Jennifer Casterline, ALLEN, Lindsay H
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Analysis of Variance Anemia - epidemiology Biological and medical sciences Biomarkers - blood Child Children & youth Creatinine - blood Female Folic Acid - blood Guatemala - epidemiology Hematocrit Hemoglobins - analysis Homocysteine - blood Humans Male Mass Screening Medical sciences Metabolic diseases Methylmalonic Acid - blood Other nutritional diseases (malnutrition, nutritional and vitamin deficiencies...) Plasma Prevalence Transcobalamins - analysis Transcobalamins - metabolism Tropical medicine Vitamin B 12 - blood Vitamin B 12 Deficiency - diagnosis Vitamin B 12 Deficiency - epidemiology Vitamin B 12 Deficiency - physiopathology
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