Calcium-dependent translocation of cytosolic phospholipase A2 in pancreatic beta-cells

Cytosolic phospholipase A(2)(cPLA(2)), an enzyme responsible for the generation of arachidonic acid, is located in the cytosolic compartment in most tissues and it translocates to membrane compartments when activated. We found that cPLA(2) distribution in pancreatic beta-cells is different from that...

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Veröffentlicht in:	Biochemical and biophysical research communications 2003-01, Vol.300 (4), p.889-893
Hauptverfasser:	Persaud, S J, Jones, P M, Roderigo-Milne, H M, Buchan, A M J, Squires, P E
Format:	Artikel
Sprache:	eng
Schlagworte:	Calcium - metabolism Cell Nucleus - metabolism Cytoplasm - enzymology Cytoplasm - metabolism Humans Hypoglycemic Agents - pharmacology Immunohistochemistry Islets of Langerhans - cytology Islets of Langerhans - drug effects Islets of Langerhans - enzymology Phospholipases A - metabolism Phospholipases A2 Protein Transport Time Factors Tolbutamide - pharmacology Tumor Cells, Cultured
Online-Zugang:	Volltext
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