Expression of chemokines and their receptors in human and simian astrocytes: Evidence for a central role of TNFα and IFNγ in CXCR4 and CCR5 modulation

Chemokines are key mediators of the selective migration of leukocytes that occurs in neurodegenerative diseases and related inflammatory processes. Astrocytes, the most abundant cell type in the CNS, have an active role in brain inflammation. To ascertain the role of astrocytes during neuropathologi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Glia 2003-03, Vol.41 (4), p.354-370
Hauptverfasser:	Croitoru-Lamoury, Juliana, Guillemin, Gilles J., Boussin, François D., Mognetti, Barbara, Gigout, Laure I., Chéret, Arnaud, Vaslin, Bruno, Le Grand, Roger, Brew, Bruce J., Dormont, Dominique
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals astrocyte Astrocytes - cytology Astrocytes - drug effects Astrocytes - metabolism Biological and medical sciences Cells, Cultured chemokine Chemokines - biosynthesis Chemokines - pharmacology CNS Fetus Fundamental and applied biological sciences. Psychology human Humans Interferon-gamma - biosynthesis Interferon-gamma - pharmacology Isolated neuron and nerve. Neuroglia Macaca fascicularis Macaca mulatta receptor Receptors, CCR5 - biosynthesis Receptors, Chemokine - biosynthesis Receptors, CXCR4 - biosynthesis RNA, Messenger - biosynthesis simian Tumor Necrosis Factor-alpha - biosynthesis Tumor Necrosis Factor-alpha - pharmacology Vertebrates: nervous system and sense organs
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!