New minor taxanes analogues from the needles of Taxus canadenis

Seven new taxanes were isolated from the needles of the Canadian yew: unusual functional groups, positions and/or stereochemical features are described. Their chemical structures were rigorously characterized by detailed high resolution NMR analyses and confirmed by high resolution Fast Atom Bombard...

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Veröffentlicht in:	Bioorganic & medicinal chemistry 2003-01, Vol.11 (2), p.293-303
Hauptverfasser:	Shi, Qing Wen, Sauriol, Françoise, Mamer, Orval, Zamir, Lolita O
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents, Phytogenic - chemistry Antineoplastic Agents, Phytogenic - isolation & purification Bridged-Ring Compounds - chemistry Bridged-Ring Compounds - isolation & purification Nuclear Magnetic Resonance, Biomolecular Paclitaxel - analogs & derivatives Paclitaxel - pharmacology Plant Leaves - chemistry Spectrometry, Mass, Fast Atom Bombardment Taxoids Taxus - chemistry
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