Interphase fluorescence in situ hybridization assay for the detection of rearrangements of the EVI-1 locus in chromosome band 3q26 in myeloid malignancies

Institut fur Medizinische Biologie der Universitaet Wien, Austria. rotraud.wieser@univie.ac.at BACKGROUND AND OBJECTIVES: Rearrangements of the EVI-1 locus in chromosome band 3q26 are associated with a poor prognosis in myeloid malignancies. To aid the diagnosis of such aberrations, and possibly dis...

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Veröffentlicht in:	Haematologica (Roma) 2003-01, Vol.88 (1), p.25-30
Hauptverfasser:	Wieser, R, Schreiner, U, Rieder, H, Pirc-Danoewinata, H, Gruner, H, Loncarevic, IF, Fonatsch, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Adult Aged Biological and medical sciences Chromosomes, Human, Pair 3 DNA-Binding Proteins - genetics Female Gene Rearrangement Hematologic and hematopoietic diseases Humans In Situ Hybridization, Fluorescence Interphase Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology Leukemia, Myeloid - genetics Leukemia, Myeloid - pathology Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Male MDS1 and EVI1 Complex Locus Protein Medical sciences Middle Aged Myelodysplastic Syndromes - genetics Myelodysplastic Syndromes - pathology Proto-Oncogenes Transcription Factors
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