Evolution of Eukaryotic Cell Cycle Regulation: Stepwise Addition of Regulatory Kinases and Late Advent of the CDKs

Protein kinases regulate a number of critical events in mitosis and meiosis. A study of the evolution of kinases involved in cell cycle control (CCC) might shed light on the evolution of the eukaryotic cell cycle. In particular, applying quantitative phylogenetic methods to key CCC kinases could pro...

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Veröffentlicht in:Current biology 2003-01, Vol.13 (2), p.173-177
Hauptverfasser: Krylov, Dmitri M., Nasmyth, Kim, Koonin, Eugene V.
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Sprache:eng
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