HPLC analysis of vitamin E isoforms in human epidermis: correlation with minimal erythema dose and free radical scavenging activity

The content and composition of different vitamin E isoforms was analyzed in normal human skin. Interestingly the epidermis contained 1% α-tocotrienol, 3% γ-tocotrienol, 87% α-tocopherol, and 9% γ-tocopherol. Although the levels of tocotrienol in human epidermis appear to be considerably lower than r...

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Veröffentlicht in:	Free radical biology & medicine 2003-02, Vol.34 (3), p.330-336
Hauptverfasser:	Fuchs, Jürgen, Weber, Stefan, Podda, Maurizio, Groth, Norbert, Herrling, Thomas, Packer, Lester, Kaufmann, Roland
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-Tocopherol - analysis Antioxidant Chromans - analysis Chromatography, High Pressure Liquid Electron Spin Resonance Spectroscopy Epidermis - chemistry EPR Erythema - metabolism Free Radical Scavengers - metabolism Free radicals Free Radicals - metabolism gamma-Tocopherol - analysis Humans Isomerism Microbial Sensitivity Tests Redox Skin Tocotrienols Vitamin E - analogs & derivatives Vitamin E - analysis Vitamin E - chemistry
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